Arid Plants

dopamine and mescaline relationship ..?

Lewis structure of mescaline, a hallucinogenic compound in peyote, and dopamine, a neurotransmitter in the mammalian brain. suggest a reason for the ability to disrupt nerve impulse mescaline .. The structure appears on the link http://www.knowledgerush.com/wiki_image/a/a0/MESCALINE.PNG http://www.bip.bham.ac.uk/osmart/msctox/dopamine.jpg

It is speculated that mescaline, along with LSD, psilocybin, 5-Meo-DMT and tryptamine bind 5-HT receptors, specifically the 5-HT 2A receptor is a receptor G protein-coupled Binding to the receptor site in the neuron activates G protein causes dissociate and are activated by GTP. The G protein complex stimulates release various physical and chemical changes in the cell. It can directly alter the sensitivity of membrane ion transport through conformational changes, stimulate ion release cell storage, and also stimulate the transcription and editing of the primary transcript with the final result of the increased ionic activity, all these methods lead to a change in the neuronal potential. In certain nerve cells, this stimulation is inhibitory in action (resulting in the perception altered edges), while in others it is excitatory, resulting in positive symptoms of hallucination "or" vision. "

[Peyote] Last of Medicine Men 3-6

Narcotic and Hallucinogenic Cacti of the New World ...

Shamanism & the sacred cactus: Ethnoarchaeological evidence for San Pedro use in northern Peru = Shamanismo & el cacto sagrado : [evidencia etnoarqueológica ... el norte del Peru] (San Diego Museum papers) ...